王奕蓉，女，副教授，博士生导师，岳麓学者（晨星A岗）。2013年本科毕业于兰州大学，生命科学与技术专业，2018年7月于北京大学取得理学博士学位，整合生命科学（生物学）专业。2018年入选国家“博士后创新人才支持计划”（博新计划），2020年7月入职湖南老员工物公司。

课题组主要研究方向为蛋白质翻译调控和RNA生物学，重点关注mRNA翻译调控的分子机制、演化规律及其与人类健康的关系。迄今以（共同）第一作者、（共同）通讯作者身份在国际著名学术期刊发表论文17篇，包括Nature Communications，PNAS，Molecular Biology and Evolution，eLife等，另参与发表论文14篇，累计引用2900余次，h-index=15。主持重点研发计划课题、国家自然科学基金等多项国家级、省部级科研项目。

主讲本科生专业核心课《基因工程》（双语课程，生物技术专业）、通识选修课《基因组学与人类健康》与研究生课程《基因组医学》。指导本科生国家级、省级大创（SIT）项目，指导本科生参加全国老员工生命科学竞赛（CULSC）、国际基因工程机器大赛（iGEM）等并多次获奖。

实验室长期招聘博士后研究人员和科研助理，欢迎对功能基因组学，RNA生物学，生物信息学和分子演化感兴趣的同学加入团队！有意向者请将简历发送至wangyirong@hnu.edu.cn。

联系方式：wangyirong@hnu.edu.cn

2020年7月-至今，伟德官网，生物公司，副教授，岳麓学者

2018年7月-2020年6月，北京大学，生命科学公司，博雅博士后，助理研究员

2013年9月-2018年7月，北京大学，前沿交叉学科研究院，整合生命科学（生物学）专业，博士

2009年9月-2013年7月，兰州大学，生命科学公司，生物技术基地班，学士

[1]国家自然科学基金-面上项目，2025年-2028年，主持，32470655

[2]国家重点研发计划-生物安全关键技术研究专项课题，2023年-2026年，主持，2023YFC2605402

[3]国家重点研发计划-政府间科技创新合作专项，2023年-2025年，项目骨干，2022YFE0132000

[4]湖南省自然科学基金青年B类（原优秀青年科学基金），2025年-2027年，主持，2025JJ40028

[5]湖南省自然科学基金青年项目，2022年-2024年，主持，2022JJ40048

[6]长沙市杰出青年科技人才培养计划，2025-2027年，主持，kq2506004

[7]长沙市自然科学基金，2022年-2023年，主持，kq2202153

[8]中国博士后创新人才支持计划，2018年-2020年，主持，BX20180004

[1]Qianlong Dai#, Lei Lou#, Xiaojie Zhu#, Haotian Zhao, Zixin Cai, Pengcheng Wei, Yaxian Zhong, Shuchang Peng, Xinyue Hu, Ruohan Sun, Xiaotian Tang, Kai Peng, Yanwen He, Feng Gu, Xiyun Deng, Yingqun Zhou, Junhua Zhou*, Yirong Wang*, Xei Xue*, and Xiaowei Guo* (2026). TIAL1 regulates the Hippo pathway through an RNA-binding independent mechanism. Oncogene, 10.1038/s41388-026-03807-8

[2]Na Liu#, Bingxue Liu#, Chun-Rui Ma#, Zixin Cai, Jin-Tao Wang, Zi-Qing Chai, Nanlin Zhu, Ting Shao, Yue-Lei Chen, Yu Lin*, Yirong Wang*, Hong Xu*, and Xiao-Long Zhou* (2025). Mammalian tRNA acetylation determines translation efficiency and tRNA quality control. Nature Communications 16(1):5496.

[3]Du Kong#, Xiaoqin Li#, Sihua Zhao#, Chenliang Wang#, Zixin Cai, Sha Song, Yifan Guo, Xiaoyu Kuang, Xianping Wang, Wenhan Liu, Peng Liu, Xiaowei Guo, Wenyan Xu, Yirong Wang, Bin Zhao, Bin Jin*, Li He*, and Xianjue Ma*. (2025). Adipose tissue-secreted Spz5 promotes distal tumor progression via Toll-6-mediated Hh pathway activation in Drosophila. The EMBO journal 10.1038/s44318-025-00489-y.

[4]Ziguang Wang#, Shuai Li#, Sheng Zhang, Tianyu Zhang, Yujie Wu, Anqi Liu, Kui Wang, Xiaowen Ji, Haiqun Cao, Yinglao Zhang, Eng-King Tan, Yongcheng Wang*, Yirong Wang*, and Wei Liu* (2024). Hosts Manipulate Lifestyle Switch and Pathogenicity Heterogeneity of Opportunistic Pathogens in the Single-cell Resolution. eLife 13:RP96789.

[5]Junhao Chen#, Chenlu Liu#, Weixuan Li#, Wenxia Zhang, Yirong Wang, Andrew G.Clark*, and Jian Lu* (2024). From sub-Saharan Africa to China: Evolutionary history and adaptation of Drosophila melanogasterrevealed by population genomics.Science Advances 10(16):eadh3425.

[6]Fan Xu#, Jia Chen#, Yingbin Li, Shilin Ouyang, Mengting Yu,Yirong Wang, Xianming Fang, Kai He, and Feng Yu* (2024). The soil emergence-related transcription factor PIF3 controls root penetration by interacting with the receptor kinase FER.Developmental Cell 59,1-14.

[7]Ping Fu, Yifan Wu, Zhiyuan Zhang, Ye Qiu,Yirong Wang, and Yousong Peng* (2024). VIGA: a one-stop tool ofr eukaryotic virus identification and genome assembly from next-generation-sequencing data. Briefings in Bioinformatics 25(1),1-10.

[8]Yirong Wang*, Xiaolu Tang, and Jian Lu* (2023). Convergent and divergent evolution of microRNA-mediated regulation in metazoans. Biological Reviews doi:10.1111/brv.13033.

[9]Tianli Chen, Mengyu Zhang, Zhaowen Ding, Jiao Hu, Jie Yang, Lei He, Jia Jia, Jingjing Yang, Junfei Yang, Xiaoxu Song, Peng Chen, Zongzhao Zhai, Jing Huang,Yirong Wang*, and Hongtao Qin* (2023). The Drosophila NPY-like system protects against chronic stress-induced learning deficit by preventing the disruption of autophagic flux. Proceedings of the National Academy of Sciences of the United States of America 120 (51):e2307632120.

[10]Sirui Zhu#, Yuanyuan Li#, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, and Feng Yu* (2023). The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Developmental Cell 58:1-17.

[11]Junqiang Liu#, Pei Zhang#, Zhongfan Zheng#, Muhammad Irfan Afridi#, Shan Zhang, Zhiqing Wan, Xiumei Zhang, Lukas Stingelin,Yirong Wang, and Haijun Tu* (2023). GABAergic signaling between enteric neurons and intestinal smooth muscle promotes innate immunity and gut defense inCaenorhabditis elegans. Immunity 56:1515-1532.

[12]Zena Cai#, Ping Fu#, Ye Qiu, Aiping Wu, Gaihua Zhang,Yirong Wang, Taijiao Jiang, Xing-Yi Ge, Haizhen Zhu and Yousong Peng* (2022). vsRNAfinder: a novel method for identifying high-confidence viral small RNAs from small RNA-Seq data. Briefings in Bioinformatics 23(6):1-7.

[13]Hong Zhang,Yirong Wang, Xinkai Wu, Xiaolu Tang, Changcheng Wu, and Jian Lu* (2021). Determinants of genome-wide distribution and evolution of uORFs in eukaryotes. Nature Communications 12(1):1076.

[14]Hong Zhang#, Yirong Wang#, Xiaolu Tang, Shengqian Dou, Yuanqiang Sun, Qi Zhang, and Jian Lu* (2021). Combinatorial regulation of gene expression by uORFs and microRNAs inDrosophila. Science Bulletin 66: 225-228.

[15]Xiaolu Tang#, Changcheng Wu#, Xiang Li#, Yuhe Song#, Xinmin Yao, Xinkai Wu, Yuange Duan, Hong Zhang, Yirong Wang, Zhaohui Qian, Jie Cui*, and Jian Lu* (2020). On the origin and continuing evolution of SARS-CoV-2. National Science Review 7(6):1012-1023.

Before 2020

[16]Hong Zhang#, Yirong Wang#, and Jian Lu* (2019). Function and evolution of upstream ORFs in eukaryotes. Trends in Biochemical Sciences 44(9): 782-794.

[17]Yirong Wang#, Hong Zhang#, and Jian Lu* (2019). Recent advances in ribosome profiling for deciphering translational regulation. Methods doi: 10.1016/j.ymeth.2019.05.011 (F1000Prime Recommended)

[18]Hong Zhang#, Yirong Wang#, Jun Li, Han Chen, Xionglei He, Huiwen Zhang, Han Liang*, and Jian Lu* (2018). Biosynthetic energy cost for amino acids decreases in cancer evolution. Nature Communications 9(1):4124. (Best Postdoctoral Fellow Poster Awards at SMBE2019) 

[19]Shiqi Luo#, Feng He#, Junjie Luo#, Shengqian Dou#, Yirong Wang#, Annan Guo, and Jian Lu* (2018). Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response. Nucleic Acids Research 46(10):5250-5268.

[20]Junjie Luo#,Yirong Wang#, Jian Yuan#, Zhilei Zhao, and Jian Lu* (2018). MicroRNA duplication accelerates the recruitment of new targets during vertebrate evolution. RNA 24(6):787-802.

[21]Yirong Wang, Junjie Luo, Hong Zhang, and Jian Lu* (2016). MicroRNAs in the same clusters evolve to coordinately regulate functionally related genes. Molecular Biology and Evolution 33(9):2232-47; author reply in 10.1093/molbev/msz121.

[1]2024年 伟德官网教学优秀奖

[2]2023年 伟德官网优秀本科生毕业论文指导教师

[3]2022年 伟德官网青年教师托举计划

[4]2018年 北京大学优秀博士毕业生

[5]2017年 北京大学董事长奖学金

[6]2016年 研究生国家奖学金